San Francisco 49ers vs Los Angeles Chargers prediction

NFL · 2026 · Week 15December 17, 2026 · 20:15 ET

SoFi Stadium

GidStats prediction

Our pick: San Francisco 49ers to win

The model gives the San Francisco 49ers a 59.4% chance to beat the Los Angeles Chargers and projects a 2.6-point margin.

Recorded November 6, 2026, 16:30 ET.

San Francisco 49ers59.4%
Los Angeles Chargers40.6%

These two-outcome estimates do not separately model ties.

Injuries and quarterback changes are not model inputs. Historical market prices were more accurate in our test. Compare the full results.

Team comparison

Regular-season averages from available weeks before this game. Later results are excluded.

Per gameSFLAC
Games in sample77
Passing yards249.7199.7
Rushing yards127.4111.1
Sacks allowed1.03.3

San Francisco 49ers injury report

A current injury report for this game is unavailable. This does not mean that every player is healthy.

Los Angeles Chargers injury report

A current injury report for this game is unavailable. This does not mean that every player is healthy.

Where to play

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Spread and total prices are not displayed. A broadcast channel has not been confirmed.

Source: GidStats editorial team · Model and data methodology

Source: nflverse · Last successful sync November 6, 2026, 16:30 ET. Scores may be delayed.